Promethazine is contraindicated in comatose states, As well as in individuals identified to generally be hypersensitive or to possess had an idiosyncratic reaction to promethazine or to other

NMS is a significant situation that can cause Demise. Prevent taking promethazine/codeine and contact your healthcare company without delay For those who have any of the subsequent signs or symptoms.

Eliminate expired, undesirable, or unused promethazine/codeine immediately by taking your drugs to an authorized DEA-registered collector or drug choose back again plan.

The MHRA has also acquired 3 case experiences describing habit especially with codeine linctus.

If you take promethazine/codeine consistently during pregnancy, your child might have withdrawal signs or symptoms that can be everyday living-threatening. Notify your Health care service provider should you took promethazine/codeine throughout your pregnancy, Specially near the stop of one's pregnancy.

This can happen Even when you choose Promethazine Hydrochloride and Codeine Phosphate Oral Alternative particularly as prescribed by your Health care supplier. Your threat of addiction, abuse, and misuse is elevated if you or a relative contains a heritage of drug or alcohol abuse or addiction, or psychological health issues.

與其它鴉片類藥物一樣，可待因的其中一個潛在的嚴重不良反應是壓抑呼吸，通常與服用過量有關，可引致死亡。

one)]. All people taken care of with opioids demand mindful checking for signs of abuse and habit, due to the fact usage of opioid analgesic and antitussive products and solutions carries the risk of dependancy even under ideal professional medical use.

The decision to reclassify codeine linctus demonstrates which the reclassification technique is successful; this will be sure that folks are only in check here a position to obtain medicines that enable them to self-treatment safely.

Scientific scientific tests of promethazine hydrochloride and codeine phosphate syrup did not involve ample numbers of topics aged get more info sixty five and above to ascertain whether they reply otherwise from younger subjects. Other described scientific practical experience has not determined differences in responses in between the aged and young patients.

No codeine linctus dose is recommended for youngsters because this drug has the potential risk of respiration troubles and various difficulties.

Promethazine administered to your pregnant lady within two months of here supply may inhibit platelet aggregation inside the new child.

Small children Postmarketing situations of respiratory check here depression, which include fatalities, have already been reported with utilization of promethazine in pediatric individuals. Concomitant more info administration with other respiratory depressants may well increase the chance of respiratory depression.

Codeine is understood for being significantly excreted through the kidney, and the potential risk of adverse reactions to this drug might be larger in patients with impaired renal operate.